Anti Cancer Medicines

Product Details:

Nintedanib, sold under the brand names BDR and Vargatef, is an oral medication used for the treatment of idiopathic pulmonary fibrosis and along with other medications for some types of non-small-cell lung cancer.

Product Details:

Dasatinib (20 Mg, 50 Mg, 70 Mg) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.  Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.  Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.  Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment. 

Uses Of Dasatinib (20 Mg, 50 Mg, 70 Mg) Tablet: 
Blood cancer (Chronic myeloid leukaemia) 

Benefits OF Dasatinib (20 Mg, 50 Mg, 70 Mg) Tablet:
In Blood cancer (Chronic myeloid leukaemia) Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects Of Dasatinib (20 Mg, 50 Mg, 70 Mg) Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Dasatinib (20 Mg, 50 Mg, 70 Mg) Abdominal pain Anemia (low number of red blood cells) Breathing problems Fatigue Fever Headache Infection Low blood platelets Musculoskeletal (bone, muscle or joint) pain Nausea Rash Vomiting.

How to use Dasatinib (20 Mg, 50 Mg, 70 Mg) Tablet: 
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet may be taken with or without food, but it is better to take it at a fixed time. 

How Dasatinib (20 Mg, 50 Mg, 70 Mg) Tablet Works: 
Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.
 
Safety Advice:
It is not known whether it is safe to consume alcohol with Dasatinib (20 Mg, 50 Mg, 70 Mg) 20mg 50mg 70mg Tablet. 

Product Details:

Varenicline (trade name Chantix and Champix) is a medication used for smoking cessation. Varenicline is also used for the treatment of dry eye disease.

The most common side-effects include nausea (feeling sick), insomnia (difficulty sleeping), abnormal dreams, headache and nasopharyngitis (inflammation of the nose and throat).

It is a high-affinity partial agonist for nAChRα4β2, a subtype of nicotinic acetylcholine receptor (nAChR) that leads to the release of the neurotransmitter dopamine in the nucleus accumbens (reward center of the brain) when activated, and therefore, has the capacity to reduce the feelings of craving and withdrawal caused by smoking cessation. In this respect it is similar to cytisine and different from the nicotinic antagonist bupropion and nicotine replacement therapies (NRTs) like nicotine patches and nicotine gum. It is estimated that varenicline successfully helps one of every eleven people who smoke remain abstinent from tobacco at six months.

It is on the World Health Organization's List of Essential Medicines. It is available as a generic medication. In 2020, it was the 275th most commonly prescribed medication in the United States, with more than 1 million prescriptions

Product Details:

XTANDI (Enzalutamide 40mg) is a prescription medicine used to treat men with prostate cancer that: 
No longer responds to a hormone therapy or surgical treatment to lower testosterone or has spread to other parts of the body and responds to a hormone therapy or surgical treatment to lower testosterone. It is not known if XTANDI is safe and effective in females or children. XTANDI is an androgen receptor inhibitor. Androgens are a group of hormones that includes testosterone. Androgen receptor inhibitors interfere with the connection between androgens and androgen receptors. This can help slow cancer cell growth

Important Safety Information
What should I tell my doctor before taking XTANDI?
Tell your doctor about all your medical conditions, including if you:Have a history of seizures, brain injury, stroke, or brain tumors.Have a history of heart disease, have high blood pressure, or have abnormal amounts of fat or cholesterol in your blood (dyslipidemia). Are pregnant or plan to become pregnant. XTANDI can cause harm to your unborn baby and loss of pregnancy (miscarriage). Have a partner who is pregnant or may become pregnant.Males who have female partners who are able to become pregnant should use effective birth control (contraception) during treatment with XTANDI and for 3 months after the last dose. Males must use a condom during sex with a pregnant female. Are breast feeding or plan to breastfeed. It is not known if XTANDI passes into your breast milk. Take other medicines. XTANDI may affect the way other medicines work, and other medicines may affect how XTANDI works. These include prescription and over-the-counter medicines, vitamins, and herbal supplements. Do not start or stop any medicine without talking to your doctor.

How should I take XTANDI?
Take XTANDI exactly as your doctor tells you. Take your prescribed dose once a day, at the same time each day. XTANDI can be taken with or without food. Swallow XTANDI capsules or tablets whole. Do not chew, dissolve, or open the capsules. Do not cut, crush or chew the tablets. Your doctor may change your dose if needed. Do not change or stop taking your prescribed dose of XTANDI without talking with your doctor first. If you are receiving gonadotropin-releasing hormone (GnRH) therapy, you should continue with this treatment while taking XTANDI unless you have had surgery to lower the amount of testosterone in your body (surgical castration). If you miss a dose of XTANDI: Take your prescribed dose as soon as you remember that day. If you miss your daily dose, take your prescribed dose at your regular time the next day. Do not take more than your prescribed dose of XTANDI each day. If you take too much XTANDI: Call your doctor or go to the nearest emergency room right away. You may have an increased risk of seizure if you take too much XTANDI.

Product Details:

Glenza Capsule (Enzalutamide 40 mg) is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Glenza Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.Enzalutamide Glenza 40mg Capsules Uses : 

Enzalutamide 40mg is utilized for the treatment of metastatic maiming safe prostate growth (prostate cancer that is impervious to therapeutic or surgical medications that lower testosterone). This medication likewise keeps the androgens from working inside the prostate disease cells. 

 

Indian Enzalutamide Capsules Side Effects: 
All meds may cause symptoms, however many individuals have no, or minor, reactions. Check with your specialist if any of these most COMMON reactions hold on or wind up noticeably annoying: 

• Icy like manifestations (eg, hack, runny or stuffy nose, wheezing, sore throat); the runs; tipsiness; cerebral pain; hot flashes; mellow back, bone, joint, or, then again muscle torment; tiredness; inconvenience resting; shortcoming. 
• Look for medicinal consideration immediately if any of these SEVERE reactions happen: Serious unfavorably susceptible responses (rash; hives; tingling; trouble breathing; snugness in the chest; swelling of the mouth, face, lips, or tongue); nervousness; back torment with leg deadness or shortcoming; changes in the measure of pee delivered; perplexity or issues thinking obviously; the diminished feeling of touch; sentiment shivering, consuming, pricking, or deadness of the skin; fever, chills, or determined sore throat; visualizations; memory issues; muscle throbs or shortcoming; pink or red pee; seizures; 
• An extreme or diligent migraine; shortness of breath; swelling of the hands, arms, legs, or feet. 

Product Details:

Bdenza  (Enzalutamide40mg) Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Bdenza 40mg Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.

In Prostate cancer Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Bdenza 40mg Capsule decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.
Bdenza 40 mg Capsule is used to treat castrate-resistant prostate cancer (CRPC), a stage where prostate cancer keeps growing even when there are very low levels of testosterone in the body. It is mainly used in patients whose disease has progressed on or after Docetaxel therapy. This medicine is not recommended for use in females, children, and adolescents.

Benefits Of Bdenza Capsule:
In Prostate cancerProstate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Bdenza 40mg Capsule decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side Effects  Of Bdenza Capsule:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Bdenza

• Headache
• Hot flashes
• Weakness
• High blood pressure
• Fatigue

Product Details:

Azel (Enzalutamide 40mg) Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Azel 40mg Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.

Benefits Of Azel Capsule:
In Prostate cancer Prostate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Azel 40mg Capsule decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side Effects Of Azel Capsule:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

How To Use Azel Capsule:
Take this medicine in the dose and duration as advised by your doctor. Azel 40mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Azel Capsule Works:
Azel 40mg Capsule is an antiandrogens. It works by blocking the effect of the natural male hormones on the growth of prostate cells.

Product Details:

Obnyx (Enzalutamide 40mg) is FDA approved generic oncology drug that is used to treat advanced forms of Prostate cancer, non-metastatic castration-resistant prostate cancer (nmCRPC).

A company statement declared that this is a drop of 70%, in comparison to the existing cost of therapy in India.

As per statement, the current MRP of Enzalutamide drug in India ranges from Rs. 70000 to Rs 80000 for a monthly therapy and can be a huge financial burden for the elderly patients as they need to continue the therapy for a long period of time. This price reduction will benefit many prostate cancer patients to adhere to the treatment.
The drug, named Enzalutamide, launched under the brand name Obnyx 40mg, will be available in soft gelatin capsules at a monthly treatment cost aprox of 357 US$.
In the U.S, Enzalutamide is sold under the Xtandi brand name.

Obnyx 40 mg capsule is usually taken as 4 capsules (4 * 40 mg = 160 mg), once a day at the same time.

According to the company statement, 1/9 Indian males have the threat of suffering from prostate cancer, which is almost 60% of males above the age of sixty-five.

Prostate cancer remains one of the major cancers in India. The drug assists the patients by decreasing the androgen hormones in their prostate glan. Enzalutamide is used to treat prostate cancer that has spread to other parts of the body in men and who have been helped by certain medical and surgical treatments that decrease testosterone levels.

Enzalutamide is a type of hormone therapy. It is a treatment for prostate cancer that has spread to other parts of the body (advanced prostate cancer)

Product Details:

Indenza 40 mg (Enzalutamide) is an androgen receptor (AR) inhibitor indicated for patients suffering from prostate cancer types such as,

• Metastatic castration-resistant prostate cancer where other chemotherapy options (docetaxel) did not work. (cancer that lowers the growth of testosterone, a male hormone)
• Metastatic castration-sensitive prostate cancer where other hormonal therapy did not work (cancer that spreads to other parts of the body)

Peculiar properties of Indenza 40 mg (Enzalutamide) that helps in slowing down the growth of prostate cancer,

• Obstructs the communication tool of cancer cells (AR signaling i.e. binding with androgen receptor and interaction with DNA)
• Hinders the unwanted growth (Cell proliferation) of androgen (testosterone)
• Induces the act of self-destruction of cells (Apoptosis)
• Reduces the risk of progression and death
• Postpones the requirement of chemotherapy

Administration of Indenza 40 mg (Enzalutamide):

Indenza 40 mg (Enzalutamide) is given orally in a 160 mg dosage (4×40 mg) once in 24 hours with or without food. If patients experience any sort of side-effects, the dosage can be modified and reduced to 120 mg (3×40 mg) or 80 mg (2×40 mg).

Once swallowed, enzalutamide is readily soluble (bio-available) in the body within 3 hours. It is metabolized in the liver and then distributed throughout the region of cancer with a high binding affinity (97%) to cancer cells. Once enzalutamide completes its activities, more than 50% of the dose is expelled from the body in between 3 to 11 days.

When should Indenza 40 mg (Enzalutamide) be avoided or used cautiously?

• If patients have a history of or experience sudden unwarranted changes in behaviour caused due to disturbances in the brain (Seizures)
• If patients are confirmed with symptoms like headache, impaired vision and low blood pressure (Posterior reversible encephalopathy syndrome)
• If patients are seen with kidney diseases (severe renal impairment and end-stage renal disease)
• If patients show signs of severe disease of the liver
• If patients are seen with a relative risk of heart diseases
• If patients are allergic to dosage and show symptoms like tongue, lip, or pharyngeal swelling (edema)
• If patients are intolerant to lactose

Side-effects of Indenza 40 mg (Enzalutamide):
Most common side-effects:

• Tiredness (Fatigue)
• Pain in the back, muscles, bones and joints
• Diarrhea
• Weakness in the muscles
• Dizziness
• Swelling (edema) in the hands and legs
• Severe headache
• Cold-like symptoms
• Anxiety or stress

Other side-effects:

• Discoloured urine in pink or red colour (Hematuria)
• Rashes on skin
• Trouble in falling asleep (insomnia)
• Trouble in breathing (pneumonia)
• Weakness in the legs
• Pain in the lower back
• High blood pressure (Hypertension)
• Burning or numbness of skin (paresthesia)
• Excitement or confusion
• Loss of memory
• Nightmares

Product Details:

Cyendiv (Nintedanib  100mg , 150mg ) is a prescription medicine used:

• To treat people with a lung disease called idiopathic pulmonary fibrosis (IPF).
• To treat people with a chronic (long lasting) interstitial lung disease in which lung fibrosis continues to worsen (progress).
• To slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD) (also known as scleroderma-associated ILD).
• It is not known if Cyendiv is safe and effective in children.

Product Details:

Invista (Dasatinib 70mg)Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.

Invista 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.

Uses Of Invista Tablet:
Blood cancer (Chronic myeloid leukaemia)

Benefits Of Invista Tablet:
In Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Invista 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects Of Invista Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. 

Safety Advice:

• It is not known whether it is safe to consume alcohol with Invista 70mg Tablet. 
• Invista 70mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. 
• Invista 70mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
• Invista 70mg Tablet may cause side effects which could affect your ability to drive.
• Take special care when driving in case you experience side effects such as dizziness and blurred vision with Invista 70mg Tablet.
• Invista 70mg Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Invista 70mg Tablet may not be needed in these patients. 

Product Details:

Retevmo (Selpercatinib 80mg) is a prescription medicine that is used to treat certain cancers caused by abnormal RET genes in adults with non-small cell lung cancer (NSCLC) that has spread, adults and children 12 years of age and older with advanced medullary thyroid cancer (MTC) or MTC that has spread who require a medicine by mouth or injection (systemic therapy), and adults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer that has spread who require a medicine by mouth or injection (systemic therapy) and who have received radioactive iodine and it did not work or is no longer working. Your healthcare provider will perform a test to make sure that Retevmo is right for you. It is not known if Retevmo is safe and effective in children younger than 12 years of age. Retevmo was approved based on the percentage of patients whose tumor size shrank or disappeared after treatment and how long the response lasted. Studies are ongoing to confirm the benefit of Retevmo for this use. Retevmo may affect both healthy cells and tumor cells, which can result in side effects, some of which can be serious. Important Facts About RETEVMO® (reh-TEHV-moh). It is also known as selpercatinib. RETEVMO is a prescription medicine that is used to treat certain cancers caused by an abnormal gene, called RET, in: adults with non-small cell lung cancer (NSCLC) that has spread. adults and children 12 years of age and older with advanced medullary thyroid cancer (MTC) or MTC that has spread, who need a medicine that can be taken by mouth or injection. adults and children 12 years of age and older with advanced thyroid cancer or thyroid cancer that has spread, who need a medicine that can be taken by mouth or injection, and who have received radioactive iodine and it did not work or is no longer working. Your doctor will perform a test to make sure that RETEVMO is right for you. It is not known if RETEVMO is safe and effective in children younger than 12 years of age. Warnings RETEVMO may cause serious side effects, including: Liver problems: Liver problems (higher levels of liver enzymes) are common with RETEVMO and may sometimes be serious. Your doctor will do blood tests before and during treatment with RETEVMO to check for liver problems. Tell your doctor right away if you get any of the following symptoms of liver problems during treatment: yellowing of your skin or the white part of your eyes (jaundice) dark, “tea-colored” urine sleepiness bleeding or bruising loss of appetite nausea or vomiting pain on the upper right side of your stomach area If you develop liver problems while taking RETEVMO, your doctor may lower your dose, stop treatment for a while, or stop treatment permanently. High blood pressure (hypertension): High blood pressure is common with RETEVMO. It may sometimes be serious. You should check your blood pressure regularly during treatment with RETEVMO. Tell your doctor if you get any of the following symptoms during treatment: confusion headaches shortness of breath dizziness chest pain Heart rhythm changes (QT prolongation) can happen. These may be serious. RETEVMO may cause very slow, very fast, or irregular heartbeats. Tell your doctor right away if you get any of the following symptoms during treatment: loss of consciousness fainting dizziness a change in the way your heart beats (heart palpitations) Bleeding problems: RETEVMO can cause bleeding, which can be serious and may lead to death. Tell your doctor if you have any signs of bleeding during treatment, including:

Product Details:

DYRONIB (Dasatinib 70mg ) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.
DYRONIB 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. 

Uses Of Sprycel Tablet:
Blood cancer (Chronic myeloid leukaemia).

Benefits Of Sprycel Tablet:
In Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. DYRONIB 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects Of Sprycel Tablet:
TMost side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Sprycel Abdominal pain Anemia (low number of red blood cells)Breathing problems, Fatigue, Fever,Headache, Infection, Low blood platelets, Musculoskeletal (bone, muscle or joint) pain Nausea Rash Vomiting.

How To Use Sprycel Tablet:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. DYRONIB 70mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Sprycel Tablet Works:
DYRONIB 70mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice:

• It is not known whether it is safe to consume alcohol with DYRONIB 70mg Tablet.
• DYRONIB 70mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. 
• DYRONIB 70mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
• DYRONIB 70mg Tablet may cause side effects which could affect your ability to drive.Take special care when driving in case you experience side effects such as dizziness and blurred vision with DYRONIB 70mg Tablet.

Product Details:

DASATRUE(Dasatinib 70 mg ) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.
DASATRUE 70 mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.

Uses Of DASATRUE Tablet:
Blood cancer (Chronic myeloid leukaemia)

Benefits Of DASATRUE Tablet:
In Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. DASATRUE 70 mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects Of DASATRUE Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Dasature Abdominal pain Anemia (low number of red blood cells)Breathing problemsFatigue, Fever, Headache, Infection, Low blood platelets, Musculoskeletal (bone, muscle or joint) pain Nausea, Rash, Vomiting.

How To Use DASATRUE Tablet:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. DASATRUE 70 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How DASATRUE Tablet Works:
DASATRUE 70 mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice:

• It is not known whether it is safe to consume alcohol with DASATRUE 70 mg Tablet. 
• DASATRUE 70 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. 
• DASATRUE 70 mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
• DASATRUE 70 mg Tablet may cause side effects which could affect your ability to drive.

Product Details:

Nintib (Nintedanib  100mg , 150mg) is a prescription medicine used:to treat people with a lung disease called idiopathic pulmonary fibrosis (IPF).to treat people with a chronic (long lasting) interstitial lung disease in which lung fibrosis continues to worsen (progress).to slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD) (also known as scleroderma-associated ILD).It is not known if Nintib is safe and effective in children.What are the possible side effects of Nintib?Nintib may cause serious side effects, including:See “What is the most important information I should know about Nintib?”liver problems. Call your doctor right away if you have unexplained symptoms such as yellowing of your skin or the white part of your eyes (jaundice), dark or brown (tea colored) urine, pain on the upper right side of your stomach area (abdomen), bleeding or bruising more easily than normal, feeling tired, or loss of appetite. Your doctor will do blood tests to check how well your liver is working before starting and during your treatment with Nintib.diarrhea, nausea, and vomiting. While you are taking Nintib, your doctor may recommend that you drink fluids or take medicine to treat these side effects. Tell your doctor if you have diarrhea, nausea, or vomiting or if these symptoms do not go away or become worse. Tell your doctor if you are taking over-the-counter laxatives, stool softeners, and other medicines or dietary supplements that can cause diarrhea.heart attack. Tell your doctor right away if you have symptoms of a heart problem. These symptoms may include chest pain or pressure, pain in your arms, back, neck or jaw, or shortness of breath.stroke. Tell your doctor right away if you have symptoms of a stroke. These symptoms may include numbness or weakness on 1 side of your body, trouble talking, headache, or dizziness.bleeding problems. Nintib may increase your chances of having bleeding problems. Tell your doctor if you have unusual bleeding, bruising, or wounds that do not heal. Tell your doctor if you are taking a blood thinner, including prescription blood thinners and over-the-counter aspirin.tear in your stomach or intestinal wall (perforation). Nintib may increase your chances of having a tear in your stomach or intestinal wall. Tell your doctor if you have pain or swelling in your stomach area.The most common side effects of Nintib are diarrhea, nausea, stomach pain, vomiting, liver problems, decreased appetite, headache, weight loss, and high blood pressure.

Indications:
Idiopathic Pulmonary FibrosisNintib is indicated for the treatment of idiopathic pulmonary fibrosis (IPF).Chronic Fibrosing Interstitial Lung Diseases with A Progressive PhenotypeNintib is indicated for the treatment of chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype [see Clinical Studies].Systemic Sclerosis-Associated Interstitial Lung DiseaseNintib is indicated to slow the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD).

Additional Information:

• Production Capacity: NA
• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

SPNIB (Dasatinib 70mg) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.
SPNIB 70 mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. 

Uses Of Spinab Tablet:
Blood cancer (Chronic myeloid leukaemia).

Benefits Of Spinab Tablet:
In Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. SPNIB 70 mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects Of Spinab Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of SPNIBAbdominal painAnemia (low number of red blood cells)Breathing problemsFatigueFeverHeadacheInfectionLow blood plateletsMusculoskeletal (bone, muscle or joint) painNauseaRashVomiting

How To Use Spinab Tablet:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. SPNIB 70 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Spinab Tablet Works:
SPNIB 70 mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice:

• It is not known whether it is safe to consume alcohol with SPNIB 70 mg Tablet. 
• SPNIB 70 mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. 
• SPNIB 70 mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
• SPNIB 70 mg Tablet may cause side effects which could affect your ability to drive.Take special care when driving in case you experience side effects such as dizziness and blurred vision with SPNIB 70 mg Tablet.

Additional Information:

• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Sprycel(Dasatinib 20mg 50mg 70mg ) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.Sprycel 20mg 50mg 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.
Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.
Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.

Uses Of Sprycel Tablet:
Blood cancer (Chronic myeloid leukaemia).

Benefits Of Sprycel Tablet:
In Blood cancer (Chronic myeloid leukaemia)Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. Sprycel 20mg 50mg 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

Side Effects Of Sprycel Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Common side effects of Sprycel Abdominal pain, Anemia (low number of red blood cells)Breathing problems, Fatigue, Fever, Headache, Infection, Low blood platelets, Musculoskeletal (bone, muscle or joint) pain, Nausea, Rash, Vomiting.

How To Use Sprycel Tablet:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sprycel 20mg 50mg 70mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Sprycel Tablet Works:
Sprycel 20mg 50mg 70mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice:

• It is not known whether it is safe to consume alcohol with Sprycel 20mg 50mg 70mg Tablet. 
• Sprycel 20mg 50mg 70mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. 
• Sprycel 20mg 50mg 70mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Additional Information:

• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

Ibrunat (Ibrutinib 140mg)contains the Drug/Molecule called “Ibrutinib”. Ibrunat is a small molecule drug that is used to bind permanently to a protein called “Bruton’s tyrosine kinase (BTK)” which is important in B cells.

Ibrunat 140 mg Uses
Ibrunat is kind of a medicine which is prescribed for treating adult patients who has the following types of blood cancers:

• Mantle cell lymphoma
• Waldenstrom’s macroglobulinemia
• Chronic Graft Versus Host Disease
• Chronic lymphocytic leukemia and
• Marginal zone lymphoma (MZL)
• Small Lymphocytic Lymphoma

How Ibrunat Ibrutinib 140 mg Capsule Works

Ibrutinib which is the active ingredient in Ibrunat 140 mg capsules, works in a manner that it blocks the activity of a specific protein called “Bruton’s tyrosine kinase”, or BTK.

Bruton’s tyrosine kinase is a protein that is found in your B cells and it sends “signals” to the other parts of the body that help B cells to survive and multiply.

But these generic ibrunat capsules block BTK & help in killing and reducing the number of cancerous B-cells. Therefore, this stops or slows the progression of cancer.

How to Take Ibrunat Capsule
It is prescribed to take Ibrunat 140 mg once in a day at about the same time every day. The dosage and duration of treatment depends on the type of blood cancer, the age of the patient, and on how severe the condition of the patient.

Moreover, it also depends on “how the patient’s body reacts to the first dose.” The Natco Ibrunat Capsules should be taken orally with a glass of water. Please remember to not to open, crush, or chew the capsules.

Side Effects of Ibrunat Capsules
Ibrunat can cause side effects like:

• Bleeding
• Leukostasis
• Infections
• Decrease the blood cell counts
• Heart problems or Liver problems.

There are chances of occurring the new cancers in people taking Ibrunat, including skin cancer & other cancers.

The most common side effects may include:

• Pneumonia
• Upper respiratory tract infection
• Diarrhea
• Feeling very tired
• nausea
• headache
• swollen hands
• ankles or feet
• being short of breath
• dizziness
• fainting
• constipation and infected nose.

Interactions with other drugs

• Some antiplatelet drugs like “Clopidogrel”, “NSAIDs like Ibuprofen / Naproxen”, “Blood thinners like Warfarin / Dabigatran” can cause bleeding / bruising with Ibrunat capsules.
• The drug called aspirin can increase the risk of bleeding if it is used with Ibrunat Ibrutinib.
• And lastly, the azole antifungals drugs such as “Itraconazole”, “Ketoconazole” can affect the removal of Ibrunat from body.

Overdose 

• You shouldn’t take more than prescribed dose.
• The patients who have received doses higher than the recommended quantity should be carefully monitored. And most importantly, don’t ever take extra dose for the missed dose.

Precaution 
The patients taking ibrunat shouldn’t take it with grapefruit or Seville oranges. Which includes eating these fruits, drinking the juice, or taking the supplements that mat contain these fruits. It is prescribed not to take these fruits because these can increase the amount of Ibrunat in blood.

Product Details:

OFEV (nintedanib 100mg 150mg) is a prescription medicine used:

• To treat people with a lung disease called idiopathic pulmonary fibrosis (IPF).
• To treat people with a chronic (long lasting) interstitial lung disease in which lung fibrosis continues to worsen (progress).
• To slow the rate of decline in lung function in people with systemic sclerosis-associated interstitial lung disease (SSc-ILD) (also known as scleroderma-associated ILD). It is not known if OFEV is safe and effective in children.

Indications:

• Idiopathic Pulmonary  is indicated for the treatment of idiopathic pulmonary fibrosis (IPF).
• Chronic Fibrosing Interstitial Lung Diseases with A Progressive PhenotypeOFEV is indicated for the treatment of chronic fibrosing interstitial lung diseases (ILDs) with a progressive phenotype [see Clinical Studies].
• Systemic Sclerosis-Associated Interstitial Lung DiseaseOFEV is indicated to slow the rate of decline in pulmonary function in patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD).

Dosage And Administration:
Testing Prior To OFEV Administration Conduct liver function tests in all patients and a pregnancy test in females of reproductive potential prior to initiating treatment with OFEV 

Recommended Dosage

• The recommended dosage of OFEV is 150 mg twice daily administered approximately 12 hours apart.
• OFEV capsules should be taken with food 

Product Details:

DASASHEEL (Dasatinib 20mg 50mg 70mg ) Tablet is used in the treatment of blood cancer (chronic myeloid leukaemia). It is used in patients whose disease could not be treated with other medications for leukaemia or who cannot take these medications because of side effects.

DASASHEEL 20mg 50mg 70mg Tablet can be taken with or without food, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Nausea, vomiting, abdominal pain and rash are some common side effects of this medicine. In some cases, it may cause increased heartbeat and low or high blood pressure, if it happens consult with your doctor. Your doctor might check your blood pressure regularly. It is advised to avoid antacid intake within 2 hours of taking this medicine. This medicine may reduce the number of blood cells in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells.

Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. You must avoid driving if you experience dizziness or blurred vision during treatment.

Uses Of Dasasheel Tablet:
Blood cancer (Chronic myeloid leukaemia)

Benefits Of Dasasheel Tablet:

• In Blood cancer (Chronic myeloid leukaemia)
• Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body's ability to fight infection. DASASHEEL 20mg 50mg 70mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated.

How To Use Dasasheel Tablet:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. DASASHEEL 20mg 50mg 70mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Dasasheel Tablet Works:
DASASHEEL 20mg 50mg 70mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Product Details:

Mebendazole 500mg is used to treat infections caused by worms. It works by keeping the worm from absorbing sugar (glucose), so that the worm loses energy and dies. This medicine is available only with your doctor's prescription.

Product Details:

Ibrunat 140 mg Uses
Ibrunat is kind of a medicine which is prescribed for treating adult patients who has the following types of blood cancers:

• Mantle cell lymphoma
• Waldenstrom’s macroglobulinemia
• Chronic Graft Versus Host Disease
• Chronic lymphocytic leukemia and
• Marginal zone lymphoma (MZL)
• Small Lymphocytic Lymphoma

Product Details:

Dasakast (dasatinib 70mg) is an oral drug indicated for patients suffering from blood cancer in both adults and children. Specifically, dasakast 50 mg (dasatinib) is used in adults with Chronic myeloid leukemia (CML) in a long-lasting (chronic) phase of the disease. Dasatinib belongs to the class of medicine known as kinase inhibitors that works its action by:

• Firstly, blocking the activities of abnormal protein
• Secondly, hindering the multiplication of cancer cells (cell-proliferation)
• Lastly, reducing blood flow to the cancer cells (angiogenesis)

Dasatinib, with the above actions, finally disrupts the spread of CML cancer cells.

Administration of Dasakast 50 mg (Dasatinib):
Dasakast (dasatinib) is given in the form of 100 mg dose (2×50 mg tablets) once daily. However, if the condition of patients does not improve, the dose is escalated to 140 mg (2×100 mg tablets) once daily. It can be taken with or without food in the morning or evening. Once swallowed, dasatinib is completely absorbed (bio-available) in 6 hours and is distributed throughout the region of cancer. It is metabolized in liver by different types of proteins and subsequently after completing its action, more than 50% of dasatinib is expelled from the body within 3 to 5 hours.

 

When should Dasakast 50 mg (Dasatinib) be avoided or used cautiously:

• In patients having a severe risk of bleeding (hemorrhage), carry out blood tests regularly
• If patients carry an infection (fever) caused due to decrease in blood cells (myelosuppression)
• If patients have symptoms like swelling, dry cough, shortness of breath or weight gain leading to the loss of fluids (fluid retention) in body
• If patients are suffering from shortness of breath, tiredness, or hypoxia) causing increase in blood pressure (Hypertension)
• If patients had a history of heart problems (heart attack or heart failure)
• If patients are seen with nausea, vomiting, weakness or cramps in the muscles, a condition where the cancerous cells are overkilled spraying their contents in the blood (tumor lysis syndrome), could be present
• If patients are pregnant or planning to get pregnant
• If patients face complications in stomach or intestine

 

Most common side-effects of Dasakast 50 mg (Dasatinib):

• Diarrhoea
• Headache
• Pain in the muscles (myalgia)
• Rashes on the skin
• Nausea
• Tiredness
• Shortness of breath
• Excessive bleeding

 

The uncommon ones are:

• Pain in the stomach and intestinal regions
• Vomiting
• Constipation
• Weight gain
• Chills
• Inconsistent heartbeat (Arrythmia)
• Fever with other signs of infection (Febrile neutropenia)
• Decrease in RBCs i.e. Hemoglobin (anemia)
• Decrease in platelets (thrombocytopenia)

Product Details:

Capmide 40mg Capsule is used in the treatment of cancer of the prostate gland. It may be also used to treat other conditions, as determined by the doctor. It works by blocking the effects of male hormones such as testosterone.

Capmide 40mg Capsule should be taken with or without food, preferably at a fixed time every day. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Headache, hot flashes, weakness and high blood pressure is very common side effect of this medicine. Other than this, yellowing of skin, loss of appetite, shortness of breath, abdominal pain, dark urine, and skin rashes might be observed as side effects. Regular blood tests are required to check your blood cells along with liver function during treatment with this medicine. It makes your skin more sensitive towards sunlight, hence take extra caution while going out.

Before taking it, tell your doctor if have diabetes, seizures, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You may be asked for regular monitoring of blood glucose level while on treatment.

Benefits Of Capmide Capsule:
In Prostate cancerProstate gland is a small walnut-sized gland that produces a fluid called seminal fluid that nourishes and transports sperms in males. The most common symptom of prostate cancer is difficulty with urination, but sometimes there are no symptoms at all. Capmide 40mg Capsule decreases or stops the growth of cancer cells by decreasing the amount of testosterone (natural hormone in males) in men. This also relieves difficulty in passing urine and makes it easier for you to urinate.

Side Effects Of Capmide Capsule:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them.

Common side effects of Capmide:

• Headache
• Hot flashes
• Weakness
• High blood pressure
• Fatigue

How To Use Capmide Capsule:
Take this medicine in the dose and duration as advised by your doctor. Capmide 40mg Capsule may be taken with or without food, but it is better to take it at a fixed time.

How Capmide Capsule works:
Capmide 40mg Capsule is an antiandrogens. It works by blocking the effect of the natural male hormones on the growth of prostate cells.

Product Details:

Dasanat (Dasatinib 50mg) Tablet is used for the treatment of Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML), a type of blood cancer that occurs due to a chromosome abnormality. It is also used for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), a type of white blood cell cancer where the bone marrow produces cancerous and immature lymphoblasts in large quantities. This medicine is not recommended for patients below 1 year of age.Side effectsMajor & minor side effects for Dasanat 50 TabletBody aches or PainBurning, numbness, tingling in the arms and feetChest painChillsCoughDizzinessHeadacheWeight gainFeverIrritation of throatUlcers or white spots in the mouthNauseaIrregular breathingIncreased sweatingUses of Dasanat 50 TabletWhat is it prescribed for?Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML)This medicine is used for the treatment of advanced and newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (Ph+ CML) in chronic phase in patients who have acquired resistance or intolerance to prior therapy.Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL)This medicine is used for the treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ ALL), a type of white blood cell cancer where the bone marrow produces cancerous lymphocytes. It is used in patients who have acquired resistance or intolerance to prior therapy. WarningsWarnings for special populationPregnancyThis medicine is not recommended for use in pregnant women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine.Breast-feedingThis medicine is not recommended for use in breastfeeding women unless absolutely necessary. The risks and benefits should be discussed with the doctor before taking this medicine. Your doctor may advise you to discontinue breastfeeding or to discontinue the medicine based on your clinical condition.General warningsGastrointestinal disordersThis medicine should be used with caution in patients having a pre-existing disorder of the stomach or the intestine due to the increased risk of worsening of the patient's condition. Replacement with a suitable alternative may be necessary based on the clinical condition.Driving or Operating machineryUse of this medicine may cause dizziness and blurring of vision. Hence, it is advised that you do not perform any activities that require high mental alertness such as driving a vehicle or operating heavy machinery during treatment with this medicine.Bonemarrow suppressionThis medicine should be used with caution in patients having conditions like thrombocytopenia, agranulocytosis, anemia, or bone marrow suppression due to the increased risk of worsening of the patient's condition. A complete blood count should be performed before initiating treatment with this medicine. Close monitoring of blood counts is recommended during treatment with this medicine. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.Internal bleeding or hemorrhageThis medicine should be used with caution due to the increased risk of internal bleeding or hemorrhages. Any symptoms such as unusual bleeding or bruising, black or tarry stools, vomiting up blood, etc. should be reported to the doctor on priority. Appropriate dose adjustments or replacement with a suitable alternative may be required based on the clinical condition.Risk of infectionsUse of this medicine may weaken the immune system and may make you more vulnerable to infections. It is advised that you avoid coming in contact with people suffering from an infection while taking this medicine.

Product Details:

Geftinib 250 mg is used to treat adults with non-small cell lung cancer (locally advanced or distance spread [metastasis]).
Geftinib 250 mg blocks a protein called ‘epidermal growth factor receptor’ (EGFR) which is involved in the growth and spread of cancer cells.

Product Details:

Azacitidine (trade name Vidaza) is a chemical analog of cytidine, a nucleoside in DNA and RNA. Azacitidine and its deoxy derivative, decitabine are used in the treatment of myelodysplastic syndrome. Both drugs were first synthesized in Czechoslovakia as potential chemotherapeutic agents for cancer.

Product Details:

Soranib (Sorafenib 200mg)  Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer.

Soranib Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Fatigue, nausea, loss of appetite, hair loss and diarrhea are some common side effects of this medicine. It might cause high blood pressure, so the doctor may ask you for a regular check-up of blood pressure. You must inform your doctor if you notice severe skin reaction such as skin rash, or any pain, swelling, and redness of your hands and feet.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or high blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses Of Soranib Tablet:

• Liver cancer
• Kidney cancer
• Thyroid cancer

Benefits Of Soranib Tablet:
In Liver cancerLiver cancer is the cancer that develops in the cells of the liver called hepatocytes. There may be no symptoms present in the early stages of the cancer but as the disease advances to later stages symptoms such as weight loss, stomach pain, vomiting and yellowed skin. Soranib Tablet kills the cancer cells and prevents further growth and spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and do not drink alcohol or smoke. Alcohol intake or smoking can worsen your condition and hinder your recovery.

Side Effects Of Soranib Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Soranib:

• Fatigue
• Nausea
• Loss of appetite
• Diarrhea
• Abdominal pain
• Hair loss
• Weight loss
• Rash
• Painful blisters on hands and feet

How To Use Soranib Tablet:
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Soranib Tablet is to be taken empty stomach.HOW SORANIB TABLET WORKSSoranib Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice:

• It is not known whether it is safe to consume alcohol with Soranib Tablet. Please consult your doctor.
• Soranib Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks.
• Soranib Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Product Details:

Sorafenat (Sorafenib 200mg) Tablet belongs to the class of medicines known as tyrosine kinase inhibitors used in the treatment of liver cancer, kidney cancer, and thyroid cancer.

Sorafenat 200mg Tablet should be taken on an empty stomach, but try to have it at the same time every day to get the most benefits. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

Fatigue, nausea, loss of appetite, hair loss and diarrhea are some common side effects of this medicine. It might cause high blood pressure, so the doctor may ask you for a regular check-up of blood pressure. You must inform your doctor if you notice severe skin reaction such as skin rash, or any pain, swelling, and redness of your hands and feet.

Before taking it, tell your doctor if you have heart disease, liver, or kidney problems or high blood pressure. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses Of Sorafenat Tablet:

• Liver cancer
• Kidney cancer
• Thyroid cancer

Benefits Of Sorafenat Tablet:
In Liver cancerLiver cancer is the cancer that develops in the cells of the liver called hepatocytes. There may be no symptoms present in the early stages of the cancer but as the disease advances to later stages symptoms such as weight loss, stomach pain, vomiting and yellowed skin. Sorafenat 200mg Tablet kills the cancer cells and prevents further growth and spread of cancer to other unaffected areas. Follow your doctor’s instructions carefully and do not drink alcohol or smoke. Alcohol intake or smoking can worsen your condition and hinder your recovery.

Side Effects Of Sorafenat Tablet:
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about themCommon side effects of Sorafenat:

• Fatigue
• Nausea
• Loss of appetite
• Diarrhea
• Abdominal pain
• Hair loss
• Weight loss
• Rash
• Painful blisters on hands and feet

How To Use Sorafenat Tablet::
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Sorafenat 200mg Tablet is to be taken empty stomach.

How Sorafenat Tablet Works:
Sorafenat 200mg Tablet is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

Safety Advice:

• It is not known whether it is safe to consume alcohol with Sorafenat 200mg Tablet.
• Sorafenat 200mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Product Details:

TYKERB (lapatinib 250mg) is indicated in combination with capecitabine for the treatment of patients with advanced or metastatic breast cancer whose tumors overexpress human epidermal growth factor receptor 2 (HER2) and who have received prior therapy including an anthracycline, a taxane, and trastuzumab. Limitations of use: Patients should have disease progression on trastuzumab prior to initiation of treatment with TYKERB in combination with capecitabine. TYKERB is indicated in combination with letrozole for the treatment of postmenopausal women with hormone-receptor positive metastatic breast cancer that overexpresses the HER2 receptor for whom hormonal therapy is indicated. TYKERB in combination with an aromatase inhibitor has not been compared to a trastuzumab-containing chemotherapy regimen for the treatment of metastatic breast cancer. 

Important Safety Warning: Hepatotoxicity has been observed in clinical trials and postmarketing experience. The hepatotoxicity may be severe and deaths have been reported. Causality of the deaths is uncertain. Contraindication: TYKERB is contraindicated in patients with known severe hypersensitivity (eg, anaphylaxis) to this product or any of its components. Decreased Left Ventricular Ejection Fraction (LVEF): TYKERB has been reported to decrease LVEF. In clinical trials, >57% of LVEF decreases occurred within the first 12 weeks of treatment. Use caution if administering to patients with conditions that could impair LVEF. Confirm normal LVEF before starting TYKERB, and continue evaluations during treatment. Hepatotoxicity: Hepatotoxicity [alanine transaminase (ALT) or aspartate transaminase (AST) >3 times the upper limit of normal (ULN) and total bilirubin >2 times the ULN] has been observed in clinical trials (<1% of patients) and postmarketing experience. The hepatotoxicity may be severe and deaths have been reported. Causality of the deaths is uncertain. The hepatotoxicity may occur days to several months after initiation of treatment. Liver function tests (transaminases, bilirubin, and alkaline phosphatase) should be monitored before initiation of treatment, every 4 to 6 weeks during treatment, and as clinically indicated. If changes in liver function are severe, therapy with TYKERB should be discontinued and patients should not be retreated with TYKERB. Patients With Severe Hepatic Impairment: If TYKERB is to be administered to patients with severe preexisting hepatic impairment, dose reduction should be considered. Diarrhea: Diarrhea has been reported during treatment with TYKERB. The diarrhea may be severe, and deaths have been reported. Diarrhea generally occurs early during treatment with TYKERB, with almost half of those patients with diarrhea first experiencing it within 6 days. This usually lasts 4 to 5 days. Lapatinib-induced diarrhea is usually low-grade, with grade 3 and 4 diarrhea occurring in <10% and <1% of patients, respectively. Prompt treatment of diarrhea with antidiarrheal agents (such as loperamide) after the first unformed stool is recommended. Severe cases of diarrhea may require administration of oral or intravenous electrolytes and fluids, use of antibiotics such as fluoroquinolones (especially if diarrhea is persistent beyond 24 hours, there is fever, or grade 3 or 4 neutropenia), and interruption or discontinuation of therapy with TYKERB. Interstitial Lung Disease/Pneumonitis: TYKERB has been associated with interstitial lung disease and pneumonitis. Patients should be monitored for pulmonary symptoms indicative of interstitial lung disease or pneumonitis. Discontinue TYKERB in patients who experience pulmonary symptoms indicative of greater than or equal to grade 3 interstitial lung disease/pneumonitis.

Product Details:

Pazopanib, sold under the brand name Votrient, is an anti-cancer medication marketed worldwide by Novartis. It is a potent and selective multi-targeted receptor tyrosine kinase inhibitor that blocks tumour growth and inhibits angiogenesis. It has been approved for renal cell carcinoma and soft tissue sarcoma by numerous regulatory administrations worldwide

It is approved by numerous regulatory administrations worldwide, including the US Food and Drug Administration (FDA) (19 October 2009), the European Union's European Medicines Agency (EMA) (14 June 2010), the United Kingdom's Medicines and Healthcare products Regulatory Agency (MHRA) (14 June 2010) and Australia's Therapeutic Goods Administration (TGA) (30 June 2010), for use as a treatment for advanced/metastatic renal cell carcinoma and advanced soft tissue sarcomas.

Product Details:

Pomalidomide is sold by Celgene Inc., in the USA, under the brand name Pomalyst. Pomalidomide is a thalidomide analogue indicated, in combination with dexamethasone, for patients with multiple myeloma (a type of blood cancer) who have received at least two prior therapies including lenalidomide and a proteasome inhibitor and have demonstrated disease progression on or within 60 days of completion of the last therapy. Pomalidomide is available under the name of Pomalid and is available in 3 different powers which are as follows Pomalid 1MG, 2MG, and 4MG.

Product Details:

• Zoledronic Acid Injection IP bone is used to treat thinning and weakening of the bone (osteoporosis) and to prevent bone complications, e.g. fractures, in adult patients due to spread of cancer from other organs to .
• Zoledronic Acid Injection IP belongs to a class of drugs known as bisphosphonates. It works by slowing bone breakdown, increasing bone density (thickness), and decreasing the amount of calcium released from the bones into the blood.
• For Intravenous Infusion Sterile, Lyophilized

Product Details:

We are offering Erlotinib Tablets IP which is a Kinase inhibitor which is primarily used to treat cell lung cancer, or pancreatic cancer when combined with a certain other medications. It works by inhibiting growth to adjacent tissues in the body so that the cancerous cells slow down, allowing the patient a better environment to recover and fight cancer naturally.

Dosage and Administration:

• Typically, an adult patient will be instructed to take between 100mg and 150mg of Erlonat (Erlotinib), at least 1 hour before any meals or snacks and 2 hours after. Unless otherwise instructed, you should always swallow each tablet whole without chewing, crushing, splitting, or dissolving the tablet in liquid. Wash tablets down with full glass of water.

Additional Information:

• Item Code: ONCLG009
• Pay Mode Terms: L/C (Letter of Credit),D/P,D/A,Other
• Port of Dispatch: Mumbai
• Production Capacity: 1000 Pieces
• Delivery Time: 3-4 days

Product Details:

Lenalidomide  (5mg, 10mg , 25mg) is a prescription medicine, used to treat adults with multiple myeloma (MM) in combination with the medicine dexamethasone, or as maintenance treatment after autologous hematopoietic stem cell transplantation (a type of stem cell transplant that uses your own stem cells). Lenalidomide  should not be used to treat people who have chronic lymphocytic leukemia (CLL) unless they are participants in a controlled clinical trial. It is not known if Lenalidomide  is safe and effective in children.What is the most important information I should know about Lenalidomide  ?Before you begin taking Lenalidomide  , you must read and agree to all of the instructions in the Lenalidomide  REMS program. Before prescribingLenalidomide  , your healthcare provider will explain the Lenalidomide  REMS program to you and have you sign the Patient-Physician Agreement Form.
Lenalidomide  may cause serious side effects, including:
Possible birth defects (deformed babies) or death of an unborn baby. Females who are pregnant or who plan to become pregnant must not takeLenalidomide  .
Lenalidomide  is similar to the medicine thalidomide which is known to cause severe life-threatening birth defects. Lenalidomide  has not been tested in pregnant females. Lenalidomide  has harmed unborn animals in animal testing.Females must not get pregnant:For at least 4 weeks before startingLenalidomide  While taking Lenalidomide  During any breaks (interruptions) in your treatment with Lenalidomide  For at least 4 weeks after stopping Lenalidomide  Females who can become pregnant:
Must have pregnancy tests weekly for 4 weeks, then every 4 weeks if your menstrual cycle is regular, or every 2 weeks if your menstrual cycle is irregular.If you miss your period or have unusual bleeding, you will need to have a pregnancy test and receive counseling.Must agree to use 2 different forms of effective birth control at the same time, for at least 4 weeks before, while taking, during any breaks (interruptions) in your treatment, and for at least 4 weeks after stoppingLenalidomide  .Talk with your healthcare provider to find out about options for effective forms of birth control that you may use to prevent pregnancy before, during, and after treatment withLenalidomide  .If you had unprotected sex or if you think your birth control has failed, stop taking Lenalidomide  immediately and call your healthcare provider right away.If you become pregnant while takingLenalidomide  , stop taking it right away and call your healthcare provider. If your healthcare provider is not available, you can call Celgene Customer Care Center at 1-888-423-5436. Healthcare providers and patients should report all cases of pregnancy to:
FDA MedWatch at 1-800-FDA-1088, andCelgene Corporation, a Bristol Myers Squibb company, at 1-888-423-5436.There is a pregnancy exposure registry that monitors the outcomes of females who take Lenalidomide  during pregnancy, or if their male partner takes Lenalidomide  and they are exposed during pregnancy. You can enroll in this registry by calling Celgene Corporation, a Bristol Myers Squibb company, at the phone number listed above.
Lenalidomide  can pass into human semen:
Males, including those who have had a vasectomy, must always use a latex or synthetic condom during any sexual contact with a pregnant female or a female that can become pregnant while takingLenalidomide  , during any breaks (interruptions) in your treatment withLenalidomide  , and for up to 4 weeks after stoppingLenalidomide  .Do not have unprotected sexual contact with a female who is or could become pregnant. Tell your healthcare provider if you do have unprotected sexual contact with a female who is or could become pregnant.

Additional Information:

• Delivery Time: Immediate
• Packaging Details: Trademark shown are property of their respective owners and we do not lay any claim on them. Parallel trade if any is conducted under WTO¿¿¿s TRIPS agreement to which India is a Signatory. On this page we have made an ¿¿¿Honest Reference¿¿¿ of this product under the Trademark Act of India and applicable rules in the Territory of India. We do not claim ownership of displayed Trade mark.

Product Details:

SUTENT (Sunitinib 12.5mg,25mg,50mg) is used to treat adults with kidney cancer that has not spread (localized) and who are at high risk of RCC coming back again after having kidney surgery.
†SUTENT is used to treat advanced kidney cancer (advanced renal cell carcinoma or RCC).
‡SUTENT is used to treat a rare cancer of the stomach, bowel, or esophagus called gastrointestinal stromal tumor (GIST) and when you have taken the medicine imatinib mesylate (Gleevec®) and it did not stop the cancer from growing or you cannot take imatinib mesylate (Gleevec®). Gleevec is a registered trademark of Novartis Pharmaceuticals Corporation.
§SUTENT is used to treat a type of pancreatic cancer known as pancreatic neuroendocrine tumors (pNET) that has progressed and cannot be treated with surgery.It is not known if SUTENT is safe and effective in children.

Important Safety Information SUTENT: can cause severe liver problems that can lead to death. Tell your healthcare provider right away if you develop any of the following signs and symptoms of liver problems during treatment with SUTENT: itchingyellow eyes or skindark urinepain or discomfort in the right upper stomach areaYour healthcare provider should do blood tests to check your liver function before you start taking and during treatment with SUTENT. Your healthcare provider may tell you to temporarily or permanently stop taking SUTENT if you develop liver problems.

SUTENT may cause serious side effects, including:Heart problems. Heart problems may include heart failure, heart attack and heart muscle problems (cardiomyopathy) that can lead to death. Tell your healthcare provider if you feel very tired, are short of breath, or have swollen feet and ankles. Your healthcare provider may stop your treatment with SUTENT if you have signs and symptoms of heart failure.Abnormal heart rhythm changes. Changes in the electrical activity of your heart called QT prolongation can cause irregular heartbeats that can be life threatening. Your healthcare provider may do electrocardiograms and blood tests (electrolytes) to watch for these problems during your treatment with SUTENT. Tell your healthcare provider immediately if:you feel faint or lightheaded, or you pass outyou feel dizzyyou feel your heart beat is irregular or fastHigh blood pressure. High blood pressure is common with SUTENT and may sometimes be severe. Follow your healthcare provider’s instructions about having your blood pressure checked regularly. Call your healthcare provider if your blood pressure is high or if you have any of the following signs or symptoms of high blood pressure:severe headachelightheadednessdizzinesschange in visionYour healthcare provider may prescribe medicine for you to treat high blood pressure, if needed. Your healthcare provider may temporarily stop your treatment with SUTENT until your high blood pressure is controlled.Bleeding problems. Bleeding is common with SUTENT, but SUTENT can also cause severe bleeding problems that can lead to death. Call your healthcare provider right away if you have any of these symptoms or a serious bleeding problem during treatment with SUTENT, including:painful, swollen stomach (abdomen)vomiting bloodblack, sticky stoolsbloody urineheadache or change in your mental statuscoughing up bloodYour healthcare provider:can tell you about other symptoms to watch formay do blood tests if needed and monitor you for bleedingSerious stomach and intestinal problems that can sometimes lead to death. Some people have had tears in their stomach or intestine (perforation) or have developed an abnormal opening between the stomach and intestine (fistula). Get medical help right away if you get stomach-area (abdominal) pain that does not go away or is severe during treatment with SUTENT.

Product Details:

Noxalk (Ceritinib 150mg) Capsule is an anti-cancer medication. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.In Depth Information on Noxalk 150mg 90 CapsulesExpert advice for Noxalk 150mg 90 Capsules.

• Noxalk Capsule is used for the treatment of thyroid cancer.
• Diarrhea may occur as a side effect. Drink plenty of fluids and inform your doctor if it doesn’t stop or if you find blood in your stools.
• Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine and for a month after you stop taking it.
• Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as severe headache, confusion, problems with your eyesight, nausea or vomiting.
• It may cause serious bleeding problem. Inform your doctor if you get headaches, stomach pain or if you notice blood in your urine or stools.
• Do not take this medicine if you are pregnant, planning to conceive or breastfeeding

Product Details:

Sorafekast (Sorafenib 200mg)GENERIC NAME:Sorafenib Tablets LP. 200 mg
QUALITATIVE AND QUANTITATIVE COMPOSITION:Each film-coated tablet contains: Sorafenlb tosylate IP Equivalent to Sorafeni x me Exclplents …
Colours: Feric oxide Red usr. NF. Titanium Dioxide IP.
The used are rystal Ge G Sodium, Sodium Lauryi Sulphate, Magnesium stearate, Titanium Dioxide, Macrogol/PEG and Ferric Oxide Red’.
DOSAGE FORM AND STRENGTH:-Oral (Fllm-coated tablets) and 200 mg
4. CLINICAL PARTICULARS:
4.1 Therapeutic Indication
For the treatment of patients with advanced renal cell carcinoma (RCC).
For hepatocellular Carcinoma (HCC).
For the treatment of patients with locally advanced or metastatic differentiated thyroid carcinoma
(DTC) refractory to radioactive iodine.
4.2 Posology and mathod of administration
Sorafenib treatment should be supervised by a physician experienced in the use of anticancer therapies.
The recommended dose of sorafenib in adults is 400 mg (two tablets of 200 mg) twice daily (equivalent to a total dally dose of 800 mg).
Treatment should continue as long as clinical benefit is observed or until unacceptable toxicity occurs.
When dose Is ry during the (HCC) and advanced renal cell carcinoma (RCC), the sorafenib dose snow be reduced to two tablets of 200 mg sorafenib once dally.
When dose ion is Y¥ during the of diffe i thyroid (DTC), the sorafenib dose should be reduced to 600 mg sorafenib daily in divided doses (two tablets of 200 mg and one tablet of 200 mg twelve hours apart). If additional dose reduction is necessary, sorafenib may be reduced to 400 mg sorafenib daily in divided doses (two tablets of 200 mg twelve hours apart), and If necessary further reduced to one tablet of 200mg once daily.
Paediatric population
The safety and efficacy of sorafenib in children and adolescents aged < 18 years have not yet been established. No data are available.
Elderly population
No dose adjustment Is required In the elderly (patients above 65 years of age).
Renal impairment
No dese adjustment Is required In patients with mild, moderate or severe renal Impairment. No data Is available in patients requiring dialysis. Monitoring of fluid balance and electrolytes in patients at risk of renal dysfunction is advised.
Hepatic impairment
No dose adjustment is required in patients with Child Pugh A or B (mild to moderate) hepatic impairment.
No data Is avallable on patients with Child Pugh C (severe) hepatic Impairment. may require temporary interruption or dose reduction
For oral use.
It is recommended that sorafenib should be administered without food or with a low or moderate fat meal. If the patient Intends to have a high-fat meal, sorafenib tablets should be taken at least 1 hour before or 2 hours after the meal. The tablets should be swallowed with a glass of water.

Product Details:

Pivikto (Alpelisib 150mg) tablets is contraindicated in patients with severe hypersensitivity to it or any of its componentsIndicationPivikto (Alpelisib 150mg) tablets is indicated in combination with fulvestrant for the treatment of postmenopausal women, and men, with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative, PIK3CA-mutated, advanced or metastatic breast cancer as detected by an FDA-approved test following progression on or after an endocrine-based regimen.Important Safety InformationAlpelisib is contraindicated in patients with severe hypersensitivity to it or any of its components.Severe Hypersensitivity: Severe hypersensitivity reactions, including anaphylaxis and anaphylactic shock, can occur in patients treated with Pivikto . Severe hypersensitivity reactions were manifested by symptoms including, but not limited to, dyspnea, flushing, rash, fever, or tachycardia. The incidence of grade 3 and 4 hypersensitivity reactions was 0.7%. Advise patients of the signs and symptoms of severe hypersensitivity reactions. Permanently discontinue Alpelisib in the event of severe hypersensitivity.Severe Cutaneous Adverse Reactions (SCARs): SCARs including Stevens-Johnson syndrome (SJS), erythema multiforme (EM), toxic epidermal necrolysis (TEN), and drug reaction with eosinophilia and systemic symptoms (DRESS) can occur in patients treated with Pivikto . In the SOLAR-1 study, SJS and EM were reported in 0.4% and 1.1% of patients, respectively. DRESS was reported in patients in the postmarketing setting. If signs or symptoms of SCARs occur, interrupt Alpelisib until the etiology of the reaction has been determined. Consultation with a dermatologist is recommended.If a SCAR is confirmed, permanently discontinue Pivikto . Do not reintroduce Alpelisib in patients who have experienced previous SCARs during Alpelisib treatment. If it is not confirmed, Alpelisib may require dose modifications, topical corticosteroids, or oral antihistamine treatment.Advise patients of the signs and symptoms of SCARs (eg, a prodrome of fever, flu-like symptoms, mucosal lesions, progressive skin rash, or lymphadenopathy).Hyperglycemia: Severe hyperglycemia, including ketoacidosis, can occur in patients treated with Pivikto . Hyperglycemia was reported in 65% of patients treated with Pivikto . Grade 3 (FPG >250-500 mg/dL) and grade 4 (FPG >500 mg/dL) hyperglycemia were reported in 33% and 3.9% of patients, respectively. Ketoacidosis was reported in 0.7% of patients (n=2) treated with Pivikto .Before initiating treatment with Pivikto , test fasting plasma glucose (FPG), HbA1c, and optimize blood glucose. After initiating treatment with Pivikto , monitor fasting glucose (FPG or fasting blood glucose) at least once every week for the first 2 weeks, then at least once every 4 weeks, and as clinically indicated. Monitor HbA1c every 3 months and as clinically indicated. If a patient experiences hyperglycemia after initiating treatment with Pivikto , monitor fasting glucose as clinically indicated, and at least twice weekly until fasting glucose decreases to normal levels. During treatment with antidiabetic medication, continue monitoring fasting glucose at least once a week for 8 weeks, followed by once every 2 weeks and as clinically indicated. Consider consultation with a health care practitioner with expertise in the treatment of hyperglycemia and counsel patients on lifestyle changes.The safety of Alpelisib in patients with type 1 and uncontrolled type 2 diabetes has not been established as these patients were excluded from the SOLAR-1 trial. Patients with a medical history of type 2 diabetes were included. Patients with a history of diabetes mellitus may require intensified diabetic treatment. Closely monitor patients with diabetes.

Product Details:

Glivec (Imatinib mesylate 400mg,100mg) Tablet belongs to the class of medicines known as tyrosine kinase inhibitors. It is used in the treatment of blood cancer (chronic myeloid leukaemia and Acute lymphocytic leukemia) and gastrointestinal stromal tumor. Glivec 400mg Tablet should be taken with food, but better to have it same time every day to get the most benefit. You should continue to take it as long as your doctor advises for it. The duration of treatment varies according to your need and response to treatment. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. The most common side effects of this medicine include edema, nausea, vomiting, muscle cramps, musculoskeletal pain, diarrhea, rash, fatigue, and abdominal pain. Let your doctor know if you experience unexpected rapid weight gain. Your doctor may advise for regular monitoring of blood cells and liver function while you are taking this medicine. Do not drive or do anything requiring mental focus if you experience dizziness and blurry vision. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. USES OF GLIVEC TABLET Blood cancer (Chronic myeloid leukaemia) Blood cancer (Acute lymphocytic leukemia) Gastrointestinal stromal tumour BENEFITS OF GLIVEC TABLET In Blood cancer (Chronic myeloid leukaemia) Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body''s ability to fight infection. Glivec 400mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated. In Blood cancer (Acute lymphocytic leukemia) Blood cancer, also called leukemia, is a cancer of the blood-forming tissues, that decreases the body''s ability to fight infection. Glivec 400mg Tablet kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells. It is a potent and very toxic medicine and you should discuss the risks and benefits with your doctor. You should avoid drinking alcohol while having this treatment and drink plenty of water to stay hydrated. In Gastrointestinal stromal tumour A gastrointestinal stromal tumor (GIST) is a type of tumor that occurs most commonly in the stomach or small intestine. The tumors develop into the specialized cells called interstitial cells of Cajal (ICCs). Glivec 400mg Tablet helps to kill the cancer cells and also stops their further growth and spread. Follow your doctor’s instructions carefully to get the most benefit. Show Less SIDE EFFECTS OF GLIVEC TABLET Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them Common side effects of Glivec Edema (swelling) Nausea Vomiting Muscle cramp Musculoskeletal (bone, muscle or joint) pain Diarrhea Rash Fatigue Abdominal pain HOW TO USE GLIVEC TABLET Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Glivec 400mg Tablet is to be taken with food.